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The Src family kinase LCK cooperates with oncogenic FLT3/ITD in cellular transformation

The non-receptor tyrosine kinase LCK belongs to the SRC family of kinases. SRC family kinases are proto-oncogenes that have long been known to play key roles in cell proliferation, motility, morphology and survival. Here we show that LCK regulates the function of the type III receptor tyrosine kinas...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Marhäll, Alissa, Kazi, Julhash U., Rönnstrand, Lars
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653865/
https://ncbi.nlm.nih.gov/pubmed/29062038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14033-4
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