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The Src family kinase LCK cooperates with oncogenic FLT3/ITD in cellular transformation
The non-receptor tyrosine kinase LCK belongs to the SRC family of kinases. SRC family kinases are proto-oncogenes that have long been known to play key roles in cell proliferation, motility, morphology and survival. Here we show that LCK regulates the function of the type III receptor tyrosine kinas...
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Publicado no: | Sci Rep |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group UK
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5653865/ https://ncbi.nlm.nih.gov/pubmed/29062038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14033-4 |
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