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The Src family kinase LCK cooperates with oncogenic FLT3/ITD in cellular transformation

The non-receptor tyrosine kinase LCK belongs to the SRC family of kinases. SRC family kinases are proto-oncogenes that have long been known to play key roles in cell proliferation, motility, morphology and survival. Here we show that LCK regulates the function of the type III receptor tyrosine kinas...

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Publicado en:Sci Rep
Main Authors: Marhäll, Alissa, Kazi, Julhash U., Rönnstrand, Lars
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653865/
https://ncbi.nlm.nih.gov/pubmed/29062038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14033-4
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