RORα-expressing T regulatory cells restrain allergic skin inflammation

Atopic dermatitis is an allergic inflammatory skin disease characterized by the production of the type 2 cytokines in the skin by type 2 innate lymphoid cells (ILC2s) and T helper 2 (T(H)2) cells, and tissue eosinophilia. Using two distinct mouse models of atopic dermatitis, we show that expression...

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Vydáno v:Sci Immunol
Hlavní autoři: Malhotra, Nidhi, Leyva-Castillo, Juan Manuel, Jadhav, Unmesh, Barreiro, Olga, Kam, Christy, O’Neill, Nicholas K., Meylan, Francoise, Chambon, Pierre, von Andrian, Ulrich H., Siegel, Richard M., Wang, Eddie C., Shivdasani, Ramesh, Geha, Raif S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912895/
https://ncbi.nlm.nih.gov/pubmed/29500225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aao6923
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