RORα-expressing T regulatory cells restrain allergic skin inflammation

Atopic dermatitis is an allergic inflammatory skin disease characterized by the production of the type 2 cytokines in the skin by type 2 innate lymphoid cells (ILC2s) and T helper 2 (T(H)2) cells, and tissue eosinophilia. Using two distinct mouse models of atopic dermatitis, we show that expression...

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Detalhes bibliográficos
Publicado no:Sci Immunol
Main Authors: Malhotra, Nidhi, Leyva-Castillo, Juan Manuel, Jadhav, Unmesh, Barreiro, Olga, Kam, Christy, O’Neill, Nicholas K., Meylan, Francoise, Chambon, Pierre, von Andrian, Ulrich H., Siegel, Richard M., Wang, Eddie C., Shivdasani, Ramesh, Geha, Raif S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912895/
https://ncbi.nlm.nih.gov/pubmed/29500225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aao6923
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