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Intramolecular Interactions Overcome Hydration to Drive the Collapse Transition of Gly(15)

Simulations and experiments show oligo-glycines, polypeptides lacking any side chains, can collapse in water. We assess the hydration thermodynamics of this collapse by calculating the hydration free energy at each of the end points of the reaction coordinate, here taken as the end-to-end distance (...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Asthagiri, D., Karandur, Deepti, Tomar, Dheeraj S., Pettitt, B. Montgomery
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912879/
https://ncbi.nlm.nih.gov/pubmed/28774177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.7b05469
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