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Protein collapse driven against solvation free energy without H‐bonds

Proteins collapse and fold because intramolecular interactions and solvent entropy, which favor collapse, outweigh solute–solvent interactions that favor expansion. Since the protein backbone actively participates in protein folding and some intrinsically disordered proteins are glycine rich, oligog...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Karandur, Deepti, Harris, Robert C., Pettitt, B. Montgomery
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815319/
https://ncbi.nlm.nih.gov/pubmed/26174309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2749
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