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Protein collapse driven against solvation free energy without H‐bonds

Proteins collapse and fold because intramolecular interactions and solvent entropy, which favor collapse, outweigh solute–solvent interactions that favor expansion. Since the protein backbone actively participates in protein folding and some intrinsically disordered proteins are glycine rich, oligog...

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Опубликовано в: :Protein Sci
Главные авторы: Karandur, Deepti, Harris, Robert C., Pettitt, B. Montgomery
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815319/
https://ncbi.nlm.nih.gov/pubmed/26174309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2749
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