Alternative splicing variant of the scaffold protein APPL1 suppresses hepatic adiponectin signaling and function

Adiponectin is an adipocyte-derived hormone with antidiabetic activities that include increasing the sensitivity of cells to insulin. Adaptor protein containing pleckstrin homology domain, phosphotyrosine-binding domain, and leucine zipper motif (APPL1) stimulates adiponectin signaling and promotes...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Galan-Davila, Amanda K., Ryu, Jiyoon, Dong, Kun, Xiao, Yang, Dai, Zhe, Zhang, Deling, Li, Zhi, Dick, Amanda M., Liu, Kevin D., Kamat, Amrita, Lu, Min, Dong, Qunfeng, Liu, Feng, Dong, Lily Q.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912452/
https://ncbi.nlm.nih.gov/pubmed/29483192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002162
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