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Cyclic GMP-AMP Synthase cGAS is the cytosolic sensor of Plasmodium falciparum genomic DNA and activates type I interferons in malaria
Innate immune receptors have a key role in the sensing of malaria and initiating immune responses. As a consequence of infection, systemic inflammation emerges and is directly related to signs and symptoms during acute disease. We have previously reported that Plasmodial DNA is the primary driver of...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5912257/ https://ncbi.nlm.nih.gov/pubmed/29212905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701048 |
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