Type I interferon induction by Neisseria gonorrhoeae: Dual requirement of cyclic GMP-AMP synthase and Toll-like receptor 4

The innate immune system is the first line of defense against Neisseria gonorrhoeae (GC). Exposure of cells to GC lipooligosaccharides induces a strong immune response, leading to type I interferon (IFN) production via TLR4/MD-2. In addition to living freely in the extracellular space, GC can invade...

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Publicado no:Cell Rep
Main Authors: Andrade, Warrison A., Agarwal, Sarika, Mo, Shunyan, Shaffer, Scott A., Dillard, Joseph P., Schmidt, Tobias, Hornung, Veit, Fitzgerald, Katherine A., Kurt-Jones, Evelyn A., Golenbock, Douglas T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5401638/
https://ncbi.nlm.nih.gov/pubmed/27264171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.05.030
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