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Cyclic GMP-AMP Synthase (cGAS) Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis
Activation of the DNA-dependent cytosolic surveillance pathway in response to Mycobacterium tuberculosis infection stimulates ubiquitin-dependent autophagy and inflammatory cytokine production, and plays an important role in host defense against M. tuberculosis. However, the identity of the host sen...
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| Veröffentlicht in: | Cell Host Microbe |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4499468/ https://ncbi.nlm.nih.gov/pubmed/26048137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.05.005 |
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