ロード中...

The DNA sensor, cyclic GMP-AMP synthase (cGAS) is essential for induction of IFN beta during Chlamydia trachomatis infection()

IFNβ has been implicated as an effector of oviduct pathology resulting from genital chlamydial infection in the mouse model. In this study, we investigated the role of cytosolic DNA and engagement of DNA sensors in IFNβ expression during chlamydial infection. We determined that TREX-1, a host 3’to 5...

詳細記述

保存先:
書誌詳細
主要な著者: Zhang, Yugen, Yeruva, Laxmi, Marinov, Anthony, Prantner, Daniel, Wyrick, Priscilla, Lupashin, Vladimir, Nagarajan, Uma M.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4212656/
https://ncbi.nlm.nih.gov/pubmed/25070851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302718
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!