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Structural dynamics is a determinant of the functional significance of missense variants

Accurate evaluation of the effect of point mutations on protein function is essential to assessing the genesis and prognosis of many inherited diseases and cancer types. Currently, a wealth of computational tools has been developed for pathogenicity prediction. Two major types of data are used to th...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Proc Natl Acad Sci U S A
मुख्य लेखकों: Ponzoni, Luca, Bahar, Ivet
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2018
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910821/
https://ncbi.nlm.nih.gov/pubmed/29610305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715896115
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