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Complementary computational and experimental evaluation of missense variants in the ROMK potassium channel
The renal outer medullary potassium (ROMK) channel is essential for potassium transport in the kidney, and its dysfunction is associated with a salt-wasting disorder known as Bartter syndrome. Despite its physiological significance, we lack a mechanistic understanding of the molecular defects in ROM...
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| Yayımlandı: | PLoS Comput Biol |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7162551/ https://ncbi.nlm.nih.gov/pubmed/32251469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007749 |
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