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CD1b tetramers identify T-cells that recognize natural and synthetic diacylated sulfoglycolipids from Mycobacterium tuberculosis
Mycobacterial cell wall lipids bind the conserved CD1 family of antigen-presenting molecules and activate T-cells via their T-cell receptors (TCRs). Sulfoglycolipids (SGLs) are uniquely synthesized by Mycobacterium tuberculosis, but tools to study SGL-specific T-cells in humans are lacking. We desig...
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| Опубликовано в: : | Cell Chem Biol |
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| Главные авторы: | , , , , , , , , , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5910231/ https://ncbi.nlm.nih.gov/pubmed/29398561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.01.006 |
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