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CD1b tetramers identify T-cells that recognize natural and synthetic diacylated sulfoglycolipids from Mycobacterium tuberculosis

Mycobacterial cell wall lipids bind the conserved CD1 family of antigen-presenting molecules and activate T-cells via their T-cell receptors (TCRs). Sulfoglycolipids (SGLs) are uniquely synthesized by Mycobacterium tuberculosis, but tools to study SGL-specific T-cells in humans are lacking. We desig...

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Библиографические подробности
Опубликовано в: :Cell Chem Biol
Главные авторы: James, Charlotte A., Yu, Krystle K. Q., Gilleron, Martine, Prandi, Jacques, Yedulla, Vijayendar R., Moleda, Zuzanna Z., Diamanti, Eleonora, Khan, Momin, Aggarwal, Varinder K., Reijneveld, Josephine F., Reinink, Peter, Lenz, Stefanie, Emerson, Ryan O., Scriba, Thomas J., Souter, Michael N. T., Godfrey, Dale I., Pellicci, Daniel G., Moody, D. Branch, Minnaard, Adriaan J., Seshadri, Chetan, Van Rhijn, Ildiko
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910231/
https://ncbi.nlm.nih.gov/pubmed/29398561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.01.006
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