CD1b tetramers identify T-cells that recognize natural and synthetic diacylated sulfoglycolipids from Mycobacterium tuberculosis

Mycobacterial cell wall lipids bind the conserved CD1 family of antigen-presenting molecules and activate T-cells via their T-cell receptors (TCRs). Sulfoglycolipids (SGLs) are uniquely synthesized by Mycobacterium tuberculosis, but tools to study SGL-specific T-cells in humans are lacking. We desig...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Chem Biol
Main Authors: James, Charlotte A., Yu, Krystle K. Q., Gilleron, Martine, Prandi, Jacques, Yedulla, Vijayendar R., Moleda, Zuzanna Z., Diamanti, Eleonora, Khan, Momin, Aggarwal, Varinder K., Reijneveld, Josephine F., Reinink, Peter, Lenz, Stefanie, Emerson, Ryan O., Scriba, Thomas J., Souter, Michael N. T., Godfrey, Dale I., Pellicci, Daniel G., Moody, D. Branch, Minnaard, Adriaan J., Seshadri, Chetan, Van Rhijn, Ildiko
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910231/
https://ncbi.nlm.nih.gov/pubmed/29398561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.01.006
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados