Llwytho...

Cardiomyocyte-specific deletion of Sirt1 gene sensitizes myocardium to ischaemia and reperfusion injury

AIMS: A longevity gene, Sirtuin 1 (SIRT1) and energy sensor AMP-activated protein kinase (AMPK) have common activators such as caloric restriction, oxidative stress, and exercise. The objective of this study is to characterize the role of cardiomyocyte SIRT1 in age-related impaired ischemic AMPK act...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cardiovasc Res
Prif Awduron: Wang, Lin, Quan, Nanhu, Sun, Wanqing, Chen, Xu, Cates, Courtney, Rousselle, Thomas, Zhou, Xinchun, Zhao, Xuezhong, Li, Ji
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909650/
https://ncbi.nlm.nih.gov/pubmed/29409011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvy033
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