Rotigaptide protects the myocardium and arterial vasculature from ischaemia reperfusion injury

AIM: Ischaemia‐reperfusion injury (IRI) causes impaired endothelial function and is a major component of the adverse effects of reperfusion following myocardial infarction. Rotigaptide increases gap junction conductance via connexin‐43. We tested the hypothesis that rotigaptide reduces experimental...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Pedersen, Christian M., Venkatasubramanian, Sowmya, Vase, Henrik, Hyldebrandt, Janus A., Contractor, Hussain, Schmidt, Michael R., Bøtker, Hans Erik, Cruden, Nicholas L., Newby, David E., Kharbanda, Rajesh K., Lang, Ninian N.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Translational Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876181/
https://ncbi.nlm.nih.gov/pubmed/26750458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12882
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