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Dicer partner protein tunes the length of miRNAs using base-mismatch in the pre-miRNA stem

Dicer partner proteins Drosophila Loquacious-PB (Loqs-PB) and human TRBP tune the length of miRNAs produced by Dicer from a subset of pre-miRNAs and thereby alter their target repertoire, by an unknown mechanism. Here, we developed a novel high-throughput method that we named Dram-seq (Dice randomiz...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Zhu, Li, Kandasamy, Suresh K, Fukunaga, Ryuya
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909426/
https://ncbi.nlm.nih.gov/pubmed/29373753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky043
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