FK506-binding protein 10 (FKBP10) regulates lung fibroblast migration via collagen VI synthesis

BACKGROUND: In idiopathic pulmonary fibrosis (IPF), fibroblasts gain a more migratory phenotype and excessively secrete extracellular matrix (ECM), ultimately leading to alveolar scarring and progressive dyspnea. Here, we analyzed the effects of deficiency of FK506-binding protein 10 (FKBP10), a pot...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Knüppel, Larissa, Heinzelmann, Katharina, Lindner, Michael, Hatz, Rudolf, Behr, Jürgen, Eickelberg, Oliver, Staab-Weijnitz, Claudia A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909279/
https://ncbi.nlm.nih.gov/pubmed/29673351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-018-0768-1
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