FK506-Binding Protein 10, a Potential Novel Drug Target for Idiopathic Pulmonary Fibrosis

Rationale: Increased abundance and stiffness of the extracellular matrix, in particular collagens, is a hallmark of idiopathic pulmonary fibrosis (IPF). FK506-binding protein 10 (FKBP10) is a collagen chaperone, mutations of which have been indicated in the reduction of extracellular matrix stiffnes...

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Détails bibliographiques
Publié dans:Am J Respir Crit Care Med
Auteurs principaux: Staab-Weijnitz, Claudia A., Fernandez, Isis E., Knüppel, Larissa, Maul, Julia, Heinzelmann, Katharina, Juan-Guardela, Brenda M., Hennen, Elisabeth, Preissler, Gerhard, Winter, Hauke, Neurohr, Claus, Hatz, Rudolf, Lindner, Michael, Behr, Jürgen, Kaminski, Naftali, Eickelberg, Oliver
Format: Artigo
Langue:Inglês
Publié: American Thoracic Society 2015
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Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595665/
https://ncbi.nlm.nih.gov/pubmed/26039104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201412-2233OC
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