A site specific model and analysis of the neutral somatic mutation rate in whole-genome cancer data

BACKGROUND: Detailed modelling of the neutral mutational process in cancer cells is crucial for identifying driver mutations and understanding the mutational mechanisms that act during cancer development. The neutral mutational process is very complex: whole-genome analyses have revealed that the mu...

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Bibliografische gegevens
Gepubliceerd in:BMC Bioinformatics
Hoofdauteurs: Bertl, Johanna, Guo, Qianyun, Juul, Malene, Besenbacher, Søren, Nielsen, Morten Muhlig, Hornshøj, Henrik, Pedersen, Jakob Skou, Hobolth, Asger
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909259/
https://ncbi.nlm.nih.gov/pubmed/29673314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2141-2
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