A site specific model and analysis of the neutral somatic mutation rate in whole-genome cancer data

BACKGROUND: Detailed modelling of the neutral mutational process in cancer cells is crucial for identifying driver mutations and understanding the mutational mechanisms that act during cancer development. The neutral mutational process is very complex: whole-genome analyses have revealed that the mu...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Bertl, Johanna, Guo, Qianyun, Juul, Malene, Besenbacher, Søren, Nielsen, Morten Muhlig, Hornshøj, Henrik, Pedersen, Jakob Skou, Hobolth, Asger
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909259/
https://ncbi.nlm.nih.gov/pubmed/29673314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2141-2
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