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Gcn4-Mediator Specificity Is Mediated by a Large and Dynamic Fuzzy Protein-Protein Complex

Transcription activation domains (ADs) are inherently disordered proteins that often target multiple coactivator complexes, but the specificity of these interactions is not understood. Efficient transcription activation by yeast Gcn4 requires its tandem ADs and four activator-binding domains (ABDs)...

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Detaylı Bibliyografya
Yayımlandı:Cell Rep
Asıl Yazarlar: Tuttle, Lisa M., Pacheco, Derek, Warfield, Linda, Luo, Jie, Ranish, Jeff, Hahn, Steven, Klevit, Rachel E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908246/
https://ncbi.nlm.nih.gov/pubmed/29562181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.02.097
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