The Heteroaryldihydropyrimidine Bay 38-7690 Induces Hepatitis B Virus Core Protein Aggregates Associated with Promyelocytic Leukemia Nuclear Bodies in Infected Cells

Heteroaryldihydropyrimidines (HAPs) are compounds that inhibit hepatitis B virus (HBV) replication by modulating viral capsid assembly. While their biophysical effects on capsid assembly in vitro have been previously studied, the effect of HAP treatment on capsid protein (Cp) in individual HBV-infec...

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Detalhes bibliográficos
Publicado no:mSphere
Main Authors: Huber, Andrew D., Wolf, Jennifer J., Liu, Dandan, Gres, Anna T., Tang, Jing, Boschert, Kelsey N., Puray-Chavez, Maritza N., Pineda, Dallas L., Laughlin, Thomas G., Coonrod, Emily M., Yang, Qiongying, Ji, Juan, Kirby, Karen A., Wang, Zhengqiang, Sarafianos, Stefan G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5907649/
https://ncbi.nlm.nih.gov/pubmed/29669885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphereDirect.00131-18
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