The Heteroaryldihydropyrimidine Bay 38-7690 Induces Hepatitis B Virus Core Protein Aggregates Associated with Promyelocytic Leukemia Nuclear Bodies in Infected Cells

Heteroaryldihydropyrimidines (HAPs) are compounds that inhibit hepatitis B virus (HBV) replication by modulating viral capsid assembly. While their biophysical effects on capsid assembly in vitro have been previously studied, the effect of HAP treatment on capsid protein (Cp) in individual HBV-infec...

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Bibliografske podrobnosti
izdano v:mSphere
Main Authors: Huber, Andrew D., Wolf, Jennifer J., Liu, Dandan, Gres, Anna T., Tang, Jing, Boschert, Kelsey N., Puray-Chavez, Maritza N., Pineda, Dallas L., Laughlin, Thomas G., Coonrod, Emily M., Yang, Qiongying, Ji, Juan, Kirby, Karen A., Wang, Zhengqiang, Sarafianos, Stefan G.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5907649/
https://ncbi.nlm.nih.gov/pubmed/29669885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphereDirect.00131-18
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