The Heteroaryldihydropyrimidine Bay 38-7690 Induces Hepatitis B Virus Core Protein Aggregates Associated with Promyelocytic Leukemia Nuclear Bodies in Infected Cells

Heteroaryldihydropyrimidines (HAPs) are compounds that inhibit hepatitis B virus (HBV) replication by modulating viral capsid assembly. While their biophysical effects on capsid assembly in vitro have been previously studied, the effect of HAP treatment on capsid protein (Cp) in individual HBV-infec...

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Udgivet i:mSphere
Main Authors: Huber, Andrew D., Wolf, Jennifer J., Liu, Dandan, Gres, Anna T., Tang, Jing, Boschert, Kelsey N., Puray-Chavez, Maritza N., Pineda, Dallas L., Laughlin, Thomas G., Coonrod, Emily M., Yang, Qiongying, Ji, Juan, Kirby, Karen A., Wang, Zhengqiang, Sarafianos, Stefan G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5907649/
https://ncbi.nlm.nih.gov/pubmed/29669885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphereDirect.00131-18
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