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Regioselective synthesis of pyridines by redox alkylation of pyridine N-oxides with malonates

ABSTRACT: A regioselective synthesis of pyridines by the addition of malonate anions to pyridine N-oxide derivatives, which have been activated by trifluoromethanesulfonic anhydride, is reported. The reaction selectively affords either 2- or 4-substituted pyridines in good yields. GRAPHICAL ABSTRACT...

詳細記述

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書誌詳細
出版年:Monatsh Chem
主要な著者: Lemmerer, Miran, Teskey, Christopher J., Kaiser, Daniel, Maulide, Nuno
フォーマット: Artigo
言語:Inglês
出版事項: Springer Vienna 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906502/
https://ncbi.nlm.nih.gov/pubmed/29681655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00706-017-2081-y
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