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TRPV1 SUMOylation regulates nociceptive signaling in models of inflammatory pain
Although TRPV1 channels represent a key player of noxious heat sensation, the precise mechanisms for thermal hyperalgesia remain unknown. We report here that conditional knockout of deSUMOylation enzyme, SENP1, in mouse dorsal root ganglion (DRG) neurons exacerbated thermal hyperalgesia in both carr...
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| Vydáno v: | Nat Commun |
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| Hlavní autoři: | , , , , , , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5906468/ https://ncbi.nlm.nih.gov/pubmed/29670121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03974-7 |
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