Pharmacokinetic and biodistribution studies of HPMA copolymer conjugates in an aseptic implant loosening mouse model

N-(2-Hydroxypropyl) methacrylamide (HPMA) copolymers were previously found to represent a versatile delivery platform for the early detection and intervention of orthopedic implant loosening. In this manuscript, we evaluated the impact of different structural parameters of the HPMA copolymeric syste...

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Publicat a:Mol Pharm
Autors principals: Wei, Xin, Li, Fei, Zhao, Gang, Chhonker, Yashpal Singh, Averill, Christine, Galdamez, Josselyn, Purdue, P. Edward, Wang, Xiaoyan, Fehringer, Edward V., Garvin, Kevin L., Goldring, Steven R., Alnouti, Yazen, Wang, Dong
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906048/
https://ncbi.nlm.nih.gov/pubmed/28343392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.7b00045
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