Human Immunodeficiency Virus Tat Protein Aids V Region Somatic Hypermutation in Human B Cells

Long-term survivors of human immunodeficiency virus (HIV) infection have been shown to have a greatly increased incidence of B cell lymphomas. This increased lymphomagenesis suggests some link between HIV infection and the destabilization of the host B cell genome, a phenomenon also suggested by the...

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Bibliographic Details
Published in:mBio
Main Authors: Wang, Xiaohua, Duan, Zhi, Yu, Guojun, Fan, Manxia, Scharff, Matthew D.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2018
Subjects:
Observation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904410/
https://ncbi.nlm.nih.gov/pubmed/29666292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02315-17
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