Lethal Zika Virus Disease Models in Young and Older Interferon α/β Receptor Knock Out Mice

The common small animal disease models for Zika virus (ZIKV) are mice lacking the interferon responses, but infection of interferon receptor α/β knock out (IFNAR(−/−)) mice is not uniformly lethal particularly in older animals. Here we sought to advance this model in regard to lethality for future c...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Marzi, Andrea, Emanuel, Jackson, Callison, Julie, McNally, Kristin L., Arndt, Nicolette, Chadinha, Spencer, Martellaro, Cynthia, Rosenke, Rebecca, Scott, Dana P., Safronetz, David, Whitehead, Stephen S., Best, Sonja M., Feldmann, Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904210/
https://ncbi.nlm.nih.gov/pubmed/29696134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2018.00117
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