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Single low-dose VSV-EBOV vaccination protects cynomolgus macaques from lethal Ebola challenge

BACKGROUND: Ebola virus (EBOV), variant Makona, was the causative agent of the 2013–2016 West African epidemic responsible for almost 30,000 human infections and over 11,000 fatalities. During the epidemic, the development of several experimental vaccines was accelerated through human clinical trial...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:EBioMedicine
Hauptverfasser: Marzi, Andrea, Reynolds, Pierce, Mercado-Hernandez, Reinaldo, Callison, Julie, Feldmann, Friederike, Rosenke, Rebecca, Thomas, Tina, Scott, Dana P., Hanley, Patrick W., Haddock, Elaine, Feldmann, Heinz
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6945200/
https://ncbi.nlm.nih.gov/pubmed/31631035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.09.055
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