Soluble Glycoprotein Is Not Required for Ebola Virus Virulence in Guinea Pigs

Ebola virus (EBOV) uses transcriptional editing to express several glycoproteins (GPs), including secreted soluble GP (sGP) and structural GP(1,2), from a single gene. Recombinant viruses predominantly expressing GP(1,2) are known to rapidly mutate and acquire an editing site predominantly expressin...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Hoenen, Thomas, Marzi, Andrea, Scott, Dana P., Feldmann, Friederike, Callison, Julie, Safronetz, David, Ebihara, Hideki, Feldmann, Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Ebola and Marburg Viruses-Research, Outbreak Management, Epidemiology and Ecology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564536/
https://ncbi.nlm.nih.gov/pubmed/25957965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv111
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