Favipiravir (T-705) Protects IFNAR(−/−) Mice against Lethal Zika Virus Infection in a Sex-Dependent Manner

Zika virus (ZIKV), a member of the Flaviviridae family, is an important human pathogen that has caused epidemics in Africa, Southeast Asia, and the Americas. No licensed treatments for ZIKV disease are currently available. Favipiravir (T-705; 6-fluoro-3-hydroxy-2-pyrazinecarboxamide) and ribavirin (...

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Udgivet i:Microorganisms
Main Authors: Matz, Keesha, Emanuel, Jackson, Callison, Julie, Gardner, Don, Rosenke, Rebecca, Mercado-Hernandez, Reinaldo, Williamson, Brandi N., Feldmann, Heinz, Marzi, Andrea
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8227069/
https://ncbi.nlm.nih.gov/pubmed/34072604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms9061178
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