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Favipiravir (T-705) Protects IFNAR(−/−) Mice against Lethal Zika Virus Infection in a Sex-Dependent Manner

Zika virus (ZIKV), a member of the Flaviviridae family, is an important human pathogen that has caused epidemics in Africa, Southeast Asia, and the Americas. No licensed treatments for ZIKV disease are currently available. Favipiravir (T-705; 6-fluoro-3-hydroxy-2-pyrazinecarboxamide) and ribavirin (...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Microorganisms
Hauptverfasser: Matz, Keesha, Emanuel, Jackson, Callison, Julie, Gardner, Don, Rosenke, Rebecca, Mercado-Hernandez, Reinaldo, Williamson, Brandi N., Feldmann, Heinz, Marzi, Andrea
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8227069/
https://ncbi.nlm.nih.gov/pubmed/34072604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms9061178
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