Cftr Modulates Wnt/β-Catenin Signaling and Stem Cell Proliferation in Murine Intestine

BACKGROUND & AIMS: Cystic fibrosis (CF) patients and CF mouse models have increased risk for gastrointestinal tumors. CF mice show augmented intestinal proliferation of unknown etiology and an altered intestinal environment. We examined the role of the cystic fibrosis transmembrane conductance r...

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Publicado en:Cell Mol Gastroenterol Hepatol
Main Authors: Strubberg, Ashlee M., Liu, Jinghua, Walker, Nancy M., Stefanski, Casey D., MacLeod, R. John, Magness, Scott T., Clarke, Lane L.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2017
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904038/
https://ncbi.nlm.nih.gov/pubmed/29675451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2017.11.013
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