Cftr Modulates Wnt/β-Catenin Signaling and Stem Cell Proliferation in Murine Intestine

BACKGROUND & AIMS: Cystic fibrosis (CF) patients and CF mouse models have increased risk for gastrointestinal tumors. CF mice show augmented intestinal proliferation of unknown etiology and an altered intestinal environment. We examined the role of the cystic fibrosis transmembrane conductance r...

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Bibliografiske detaljer
Udgivet i:Cell Mol Gastroenterol Hepatol
Main Authors: Strubberg, Ashlee M., Liu, Jinghua, Walker, Nancy M., Stefanski, Casey D., MacLeod, R. John, Magness, Scott T., Clarke, Lane L.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904038/
https://ncbi.nlm.nih.gov/pubmed/29675451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2017.11.013
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