Cftr Modulates Wnt/β-Catenin Signaling and Stem Cell Proliferation in Murine Intestine

BACKGROUND & AIMS: Cystic fibrosis (CF) patients and CF mouse models have increased risk for gastrointestinal tumors. CF mice show augmented intestinal proliferation of unknown etiology and an altered intestinal environment. We examined the role of the cystic fibrosis transmembrane conductance r...

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Publicat a:Cell Mol Gastroenterol Hepatol
Autors principals: Strubberg, Ashlee M., Liu, Jinghua, Walker, Nancy M., Stefanski, Casey D., MacLeod, R. John, Magness, Scott T., Clarke, Lane L.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2017
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904038/
https://ncbi.nlm.nih.gov/pubmed/29675451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2017.11.013
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