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Defective goblet cell exocytosis contributes to murine cystic fibrosis–associated intestinal disease

Cystic fibrosis (CF) intestinal disease is associated with the pathological manifestation mucoviscidosis, which is the secretion of tenacious, viscid mucus that plugs ducts and glands of epithelial-lined organs. Goblet cells are the principal cell type involved in exocytosis of mucin granules; howev...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Liu, Jinghua, Walker, Nancy M., Ootani, Akifumi, Strubberg, Ashlee M., Clarke, Lane L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362271/
https://ncbi.nlm.nih.gov/pubmed/25642775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI73193
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