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Defective goblet cell exocytosis contributes to murine cystic fibrosis–associated intestinal disease

Cystic fibrosis (CF) intestinal disease is associated with the pathological manifestation mucoviscidosis, which is the secretion of tenacious, viscid mucus that plugs ducts and glands of epithelial-lined organs. Goblet cells are the principal cell type involved in exocytosis of mucin granules; howev...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Liu, Jinghua, Walker, Nancy M., Ootani, Akifumi, Strubberg, Ashlee M., Clarke, Lane L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362271/
https://ncbi.nlm.nih.gov/pubmed/25642775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI73193
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