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Defective goblet cell exocytosis contributes to murine cystic fibrosis–associated intestinal disease

Cystic fibrosis (CF) intestinal disease is associated with the pathological manifestation mucoviscidosis, which is the secretion of tenacious, viscid mucus that plugs ducts and glands of epithelial-lined organs. Goblet cells are the principal cell type involved in exocytosis of mucin granules; howev...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Liu, Jinghua, Walker, Nancy M., Ootani, Akifumi, Strubberg, Ashlee M., Clarke, Lane L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362271/
https://ncbi.nlm.nih.gov/pubmed/25642775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI73193
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