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Pharmacokinetic–pharmacodynamic modelling of neutrophil response to G‐CSF in healthy subjects and patients with chemotherapy‐induced neutropenia

AIM: The objective of the present study was to use pharmacokinetic–pharmacodynamic modelling to characterize the effects of chemotherapy on the granulopoietic system and to predict the absolute neutrophil counts (ANCs) for patients with chemotherapy‐induced neutropenia treated with filgrastim and pe...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Melhem, Murad, Delor, Isabelle, Pérez‐Ruixo, Juan Jose, Harrold, John, Chow, Andrew, Wu, Liviawati, Jacqmin, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5903247/
https://ncbi.nlm.nih.gov/pubmed/29318653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13504
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