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Pharmacokinetic–pharmacodynamic modelling of neutrophil response to G‐CSF in healthy subjects and patients with chemotherapy‐induced neutropenia

AIM: The objective of the present study was to use pharmacokinetic–pharmacodynamic modelling to characterize the effects of chemotherapy on the granulopoietic system and to predict the absolute neutrophil counts (ANCs) for patients with chemotherapy‐induced neutropenia treated with filgrastim and pe...

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Dades bibliogràfiques
Publicat a:Br J Clin Pharmacol
Autors principals: Melhem, Murad, Delor, Isabelle, Pérez‐Ruixo, Juan Jose, Harrold, John, Chow, Andrew, Wu, Liviawati, Jacqmin, Philippe
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5903247/
https://ncbi.nlm.nih.gov/pubmed/29318653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13504
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