Quantification of Radiation Injury on Neutropenia and the Link between Absolute Neutrophil Count Time Course and Overall Survival in Nonhuman Primates Treated with G-CSF

PURPOSE: To model absolute neutrophil count (ANC) suppression in response to acute radiation (AR) exposure and evaluate ANC time course as a predictor of overall survival (OS) in response to AR exposure with or without treatment with granulocyte colony-stimulating factor in nonhuman primates. METHOD...

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Detalhes bibliográficos
Publicado no:Pharm Res
Main Authors: Harrold, John, Gisleskog, Per Olsson, Delor, Isabelle, Jacqmin, Philippe, Perez-Ruixo, Juan Jose, Narayanan, Adimoolam, Doshi, Sameer, Chow, Andrew, Yang, Bing-Bing, Melhem, Murad
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2020
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7242243/
https://ncbi.nlm.nih.gov/pubmed/32440783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-020-02839-3
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