Developmental pharmacogenetics of CYP2C19 in neonates and young infants: omeprazole as a probe drug

AIMS: Although substantial progress has been made in understanding of ontogeny of drug metabolism, there is still a gap of knowledge in developmental pharmacogenetics in neonates. We hypothesized that both age and pharmacogenetics might explain the developmental pattern of CYP2C19. We conducted a po...

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Bibliographic Details
Published in:Br J Clin Pharmacol
Main Authors: Zhao, Wei, Leroux, Stéphanie, Biran, Valérie, Jacqz‐Aigrain, Evelyne
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
Subjects:
Pharmacogenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5903239/
https://ncbi.nlm.nih.gov/pubmed/29377228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13526
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