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A Population and Developmental Pharmacokinetic Analysis To Evaluate and Optimize Cefotaxime Dosing Regimen in Neonates and Young Infants

Cefotaxime is one of the most frequently prescribed antibiotics for the treatment of Gram-negative bacterial sepsis in neonates. However, the dosing regimens routinely used in clinical practice vary considerably. The objective of the present study was to conduct a population pharmacokinetic study of...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Leroux, Stéphanie, Roué, Jean-Michel, Gouyon, Jean-Bernard, Biran, Valérie, Zheng, Hao, Zhao, Wei, Jacqz-Aigrain, Evelyne
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075068/
https://ncbi.nlm.nih.gov/pubmed/27572399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01045-16
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