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Pilot Study of Model-Based Dosage Individualization of Ganciclovir in Neonates and Young Infants with Congenital Cytomegalovirus Infection

Newborns with congenital cytomegalovirus (CMV) infection are at high risk for developing permanent sequelae. Intravenous ganciclovir therapy is frequently used for the treatment of congenital CMV infection. A target area under the concentration-time curve from 0 to 24 h (AUC(0–24)) of 40 to 50 μg ·...

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Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Dong, Qian, Leroux, Stephanie, Shi, Hai-Yan, Xu, Hai-Yan, Kou, Chen, Khan, Muhammad Wasim, Jacqz-Aigrain, Evelyne, Zhao, Wei
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5923132/
https://ncbi.nlm.nih.gov/pubmed/29507070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00075-18
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