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Developmental pharmacogenetics of CYP2C19 in neonates and young infants: omeprazole as a probe drug

AIMS: Although substantial progress has been made in understanding of ontogeny of drug metabolism, there is still a gap of knowledge in developmental pharmacogenetics in neonates. We hypothesized that both age and pharmacogenetics might explain the developmental pattern of CYP2C19. We conducted a po...

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Publicat a:Br J Clin Pharmacol
Autors principals: Zhao, Wei, Leroux, Stéphanie, Biran, Valérie, Jacqz‐Aigrain, Evelyne
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5903239/
https://ncbi.nlm.nih.gov/pubmed/29377228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13526
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