A catalytic fluoride-rebound mechanism for C(sp(3))-CF(3) bond formation

The biological properties of trifluoromethyl compounds have led to their ubiquity in pharmaceuticals, yet their chemical properties have made their preparation a substantial challenge, necessitating innovative chemical solutions. We report the serendipitous discovery of a borane-catalyzed formal C(s...

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Xehetasun bibliografikoak
Argitaratua izan da:Science
Egile Nagusiak: Levin, Mark D., Chen, Tiffany Q., Neubig, Megan E., Hong, Cynthia M., Theulier, Cyril A., Kobylianskii, Ilia J., Janabi, Mustafa, O’Neil, James P., Toste, F. Dean
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902185/
https://ncbi.nlm.nih.gov/pubmed/28642435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aan1411
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