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Tim-3, Lag-3, and TIGIT

Co-inhibitory receptors play a key role in regulating T cell responses and maintaining immune homeostasis. Their inhibitory function prevents autoimmune responses but also restricts the ability of T cells to mount effective immune responses against tumors or persistent pathogens. T cells express a m...

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Détails bibliographiques
Publié dans:Curr Top Microbiol Immunol
Auteurs principaux: Joller, Nicole, Kuchroo, Vijay K.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902028/
https://ncbi.nlm.nih.gov/pubmed/28900677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/82_2017_62
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