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TIGIT has T cell intrinsic inhibitory functions
Costimulatory molecules regulate the functional outcome of T cell activation and disturbance of the balance between activating and inhibitory signals results in increased susceptibility to infection or the induction of autoimmunity. Like the well-characterized CD28/CTLA-4 costimulatory pathway, a ne...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3128994/ https://ncbi.nlm.nih.gov/pubmed/21199897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003081 |
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