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The TIGIT/CD226 axis regulates human T cell function
TIGIT is a newly identified receptor expressed on T cells that binds to CD155 on the dendritic cell surface driving them to a more tolerogenic phenotype. Given that TIGIT contains an ITIM motif in its intracellular domain and considering the potential importance of the TIGIT/CD226 pathway in human a...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3324669/ https://ncbi.nlm.nih.gov/pubmed/22427644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103627 |
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