Expansion of circulating peripheral TIGIT+CD226+ CD4 T cells with enhanced effector functions in dermatomyositis

BACKGROUND: T cell Ig and ITIM domain (TIGIT)/CD226 pathway has a critical role in regulating T cell responses and has come to the forefront in cancer as a promising immunotherapeutic target. However, its role in autoimmune diseases is just beginning to be elucidated. Dermatomyositis (DM) is an auto...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Arthritis Res Ther
Prif Awduron: Li, Wenli, Deng, Chuiwen, Yang, Hanbo, Lu, Xin, Li, Shanshan, Liu, Xia, Chen, Fang, Chen, Lida, Shu, Xiaoming, Zhang, Lu, Liu, Qingyan, Wang, Guochun, Peng, Qinglin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2021
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7791775/
https://ncbi.nlm.nih.gov/pubmed/33413573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-020-02397-4
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